Question

Which of the following statements is FALSE regarding TFIID?

A. It contains a TATA binding protein
B. It aids in initiation of transcription
C. It binds to the core promoter
D. It binds to the TATA box
E. It is a specific regulatory transcriptional activator protein

Answer 1

E. It is a specific regulatory transcriptional activator protein

Step-by-step explanation:

TFIID is a transcription coactivator protein complex. It is a protein complex of about 12 proteins and includes TATA-binding protein (TBP) and certain TBP-associated factors, or TAFs. TFIID is required for transcription as it acts as an intermediate between the DNA-binding transcription activators and the Pol II complex. Some TAFs of TFIID share a resemblance with histone proteins and displace nucleosomes during the activation of transcription.