Question

Compare and contrast intracellular receptors and plasma membrane receptors; consider the chemical nature of the ligands (i.e. chemical messengers), location of the receptors in/on the cell, and consequences of ligand-receptor binding. Provide an example of each type of receptor.

Answer 1

Explanation: They both require the binding of Ligand.

Differences:

Intracellular receptor is located in cytosol. It can be found in the nucleus. It leads to slower responses related to gene transcription. They are steroids. Ligands are lipophilic, small, uncharged; diffuse through membrane and bind to receptor.

Plasma membrane receptor-

The Ligands are hydrophobic and don't have to be small and uncharged; bind only to membrane receptor. Extracellular signaling molecule binds to cell membrane receptor and triggers rapid cellular response (protein hormone)