Question

What is the best explanation for the presentation of gout in this individual and please explain why the other choices are not consistent with the data or what additional information you may need to decide the root cause?

1. overproduction of purines
2. decreased salvage of purines
3. decreased urinary excretion of uric acid

Answer 1

Answer: OPTION 3 - decreased urinary excretion of uric acid

Step-by-step explanation:

Gout is an extremely painful condition where the joints are inflamed, especially the big toe, caused by a metabolic defect resulting in the accumulation of URIC ACID in the blood and the deposition of urates around the joints.

Additional information:

Uric acids belong to the PURINE group, it occurs in very small amount in the urine of some animals and usually nontoxic.

Options 1 and 2 does not explain gout