Question

A 2-year-old girl with a recent history of idiopathic nausea and vomiting was prescribed promethazine (Phenergan) by her primary care provider. The immaturity of this child's gastrointestinal system will primarily influence what aspect of pharmacokinetics? Absorption Distribution Metabolism Elimination

Answer 1

Absorption

Step-by-step explanation:

This is because gastric emptying and intestinal motility greatly affect the 2- year- old drug absorption; the GI tract is less directly involved in distribution, metabolism and elimination.

Answer 2

The correct answer is- absorption.

Explanation:

The Phenergan is the drug that is used to treat nausea, pain vomiting like symptoms. Idiopathic nausea and vomiting affect gastric emptying and intestinal motility.

The absorption of the child's drug is greatly affected by the intestinal motility and gastric emptying. There is no direct involvement or if there is than its very less in elimination, metabolism, and distribution.

Thus, the correct answer is- absorption.