Question

What effect would you predict acrylamide treatment would have on the mechanical rigidity of a keratinocyte (skin cell)?

Explain your answer.
A. Disrupting intermediate filaments will result in cells that are less susceptible to mechanical forces. In the case of the keratinocytes, disrupting keratin, a key IF in these cells, would result in the production of microfilaments and thus very tough cells.
B. More force would need to be applied using the magnetic beads to damage them or change their shape.
C. Disrupting intermediate filaments will result in cells that are more susceptible to mechanical forces. In the case of the keratinocytes, disrupting keratin, a key IF in these cells, would result in very fragile cells. Less force would need to be applied using the magnetic beads to damage them or change their shape.
D. Disrupting intermediate filaments will have no effect on their susceptibility to mechanical forces. In the case of the keratinocytes, disrupting keratin, a key IF in these cells, would not change the amount of force needed to be applied using the magnetic beads to damage them or change their shape.

Answer 1

C is surely the answer

C. Disrupting intermediate filaments will result in cells that are more susceptible to mechanical forces. In the case of the keratinocytes, disrupting keratin, a key IF in these cells, would result in very fragile cells. Less force would need to be applied using the magnetic beads to damage them or change their shape.