Answer: 0.000583 ml of Neupogen for one dose
Explanation:
To determine how many milliliters (ml) the nurse should administer for one dose of Neupogen, you can use the following calculation:
1. First, calculate the total amount of Neupogen needed for one dose:
Total Neupogen per dose = 175 mcg (as ordered)
2. Next, you need to convert the dose from micrograms (mcg) to milligrams (mg) because the drug label specifies the concentration in milligrams per milliliter (mg/ml).
To do this, remember that 1 milligram (mg) is equal to 1000 micrograms (mcg):
175 mcg = 175 mcg / 1000 = 0.175 mg
3. Now, you have the dose in milligrams. To find out how many milliliters of Neupogen to administer, divide the dose in milligrams by the concentration of Neupogen per milliliter:
Dose in ml = Total Neupogen per dose (mg) / Concentration of Neupogen (mg/ml)
Dose in ml = 0.175 mg / 300 mg/ml
4. Calculate the dose in milliliters:
Dose in ml = 0.000583 ml
So, the nurse should administer approximately 0.000583 ml of Neupogen for one dose, which is a very small amount. It's important to ensure precise measurement when dealing with such small doses, and specialized equipment like insulin syringes with very fine graduations may be needed for accuracy.