Question

19% of a certain population of students at Hardy-Weinberg equilibrium is affected by an autosomal dominant condition called ‘lazybuttness’, which causes them to skip important lectures. What is the frequency of the students not affected with the ‘lazybuttness' in this population?

Answer 1

81%

Explanation:

Let 'L' be the dominant and 'l' e the recessive allele for ‘lazybuttness’.

Since ‘lazybuttness’ is an autosomal dominant condition, the 19% of students affected by the condition correspond to the homozygous dominant (LL) and heterozygous (Ll) genotypes. Therefore, the rest of the population has the homozygous recessive genotype (ll) and is not affected. The frequency of students not affected is:

F = 100% - 19% = 81%