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As with any drug, aspirin (acetylsalicylic acid) must remain in the bloodstream long enough to be effective. Assume that the removal of aspirin from the bloodstream into the urine is a first-order reaction, with a half-life of about 3 hours. The instructions on an aspirin bottle say to take 1 or 2 tablets every 4 hours. If a person takes 1 aspirin tablet, how much aspirin remains in the bloodstream when it is time for the second dose? (A standard tablet contains 400. mg of aspirin.)

User Achmed
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Answer:

180 mg

Step-by-step explanation:

For a first-order reaction, we can calculate the amount of aspirine (A) at a certain time (t) using the following expression.


A=A_(0).e^(-k.t)

where,

k: rate constant

A₀: initial amount

If we know the half-life (
t_(1/2))
we can calculate the rate constant.


k=(ln2)/(t_(1/2)) =(ln2)/(3h) =0.2h^(-1)

When t = 4 h and A₀ = 400 mg, A is:


A=400mg.e^{-0.2h^(-1)* 4h} =180mg

User Stenyg
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