The size of the membrane proteins is a factor that has the greatest effect on the number of molecules.
Step-by-step explanation:
ATPs are formed by mitochondria in Oxidative Phosphorylation. The transport chain of electrons is composed of four protein complexes that helps in passing the H+ ions from the membrane of mitochondria.
The large molecules of hydrogen are pumped by the first complex that activates the activity of protein to pass four large molecules through the inner membrane. The number of molecules of ATP produced by mitochondria is related to the proton numbers that has been pumped.