Question

Joint destruction in rheumatoid arthritis occurs by an obscure process. The cellular changes, however, have been documented. Place this process in the correct order.

1. Immune complexes phagocytized, releasing lysosomal enzymes2. Neutrophils, macrophages, and lymphocytes arrive3. Vasodilation and joint swelling4. Inflammatory response5. Reactive hyperplasia of synovial cells and subsynovial tissues6. Destructive changes in joint cartilage

Answer 1

The correct answer is "1 - 5 - 2 - 4 - 3 - 6"

Step-by-step explanation:

Rheumatoid Arthritis is a disease caused by the autoimmune system when it recognizes the body's own tissues as viruses/bacteries and attacks the small joints at the wrists, hand and feet. After the immune system decides that there is a threat, lysosomal enzymes are released which are digestive enzyemes. These reactions cause reactive hyperplasia which is triggered by an infection or bacteria/virus presence. Then neutrophils, macrophages and lymphocytes release enzymes that consumes pathogens and release inflammatory substances into the bloodstream. This causes inflammation and swelling of the joints. And in time these effects the cartilages at the joints start to get damaged. I hope this answer helps.