Answer:
3rd Century B.C.E
Step-by-step explanation:
Anti-Semitism refers to the act of hostility, discrimination , or prejudice against Jewish people.
The spread of antisemitism can be tracked back to Alexandria in 3rd Century B.C.E. At that time, many Jewish people were targeted and made as slaves by the Egyptians.
The latest biggest act of antisemitism probably occurred during world war II. At that time, Nazi Germany actively hunting down Jewish people and committed mass murder over them.