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The specialized region of a chromosome where the sister chromatids are joined; it is critical for proper alignment and separation of sister chromatids during mitosis.

User MrBerta
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Answer:

Centromere

Step-by-step explanation:

The centromere is a constricted region of the chromosome where sister chromatids are joined together.

At the metaphase stage during cell division, the microtubules of the spindle fiber attach to the kinetochore, a complex of proteins associated with the centromere. Hence, without the centromere, cells cannot divide properly.

User Arnbobo
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