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which of the following aspects of the international situation in early sixteenth century southwest Asia is most relevant to understand sultan selims letter

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The correct answer to this question is The Ottoman and Safavid empires fought numerous wars for control over Iraq, Syria, and other regions of the Middle East.

The Ottoman-Safavid War of 1623-1639 was the latest in a series of conflicts between the Ottoman Empire and Safavid Persia, then the two major powers of West Asia, over Mesopotamian control.

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