For all problems, you may assume the Sickle Cell locus is in Hardy Weinberg equilibrium. Also, the term carrier will imply the person has a particular allele in his/her genotype, but is not affected with the condition. SECTION 01 - COMPUTING GENOTYPE FREQUENCIES USING HARDY WEINBERG EQUILIBRIUM
Problem 1. If the HbA allele frequency is 0.57, compute the HbA/HbA, HbA/HbS, and HbS/HbS genotype frequencies.
Problem 2. If the HbA allele frequency is 0.257, compute the HbA/HbA, HbA/HbS, and HbS/HbS genotype frequencies.
Problem 3. If the HbA allele frequency is 0.453, compute the HbA/HbA, HbA/HbS, and HbS/HbS genotype frequencies.
Problem 4. If the HbS allele frequency is 0.599, compute the HbA/HbA, HbA/HbS, and HbS/HbS genotype frequencies.
Problem 5. If the HbA allele frequency is 0.823, compute the HbA/HbA, HbA/HbS, and HbS/HbS genotype frequencies.