Answer:
D. Time and quality
Step-by-step explanation:
Science is the study of everything around us from Planets and the Universe to even the smallest electrons. The Only thing that can change the way we define Science would be Time and Quality. As time progresses our understanding and knowledge of our universe goes expanding. This can lead to groundbreaking quality discoveries. These discoveries are ultimately what can change the way we define Science since they are not yet known to us and therefore are a mystery with unknown consequences.