Specifically, urease catalyzes the hydrolysis of urea to produce ammonia and carbamate, the carbamate produced is subsequently degraded by means of spontaneous hydrolysis to produce another molecule of ammonia and carbonic acid. [1] Urease activity tends to increase the pH of the medium in which it is due to the production of ammonia. It is produced by bacteria, fungi and several higher plants. Urease, functionally, belongs to the superfamily of amidohydrolases and phosphotriesterases. [2]