Question

Draw the major organic substitution product(s) for (2R,3S)-2-bromo-3-methylpentane reacting with the given nucleophile. Indicate the stereochemistry, including H\'s, at each stereogenic center. Omit any byproducts.

Answer 1

The final product of the reaction is (2S,3S)-2-ethoxy-3-methylpentane.

Step-by-step explanation:

The given reaction undergoes
`S_(N)2` mechanism in which the nucleophile attacks the backside and it is substituted by the elimination of bromine.

Due to the backside attack of nucleophile , the inverse in stereo-chemistry is observed.

After the substitution of ethoxy group, the configuration is assigned according to the priority it shows clock wise direction(R) - configuration.

When hydrogen faces the front side , it results shows inverse configuration i.e, S- configuration.

The chemical reaction is as follows.