Step-by-step explanation:
The main reason humans have only been to the mariana trech twice is because of the pressure in the water that increases as you go deeper. The pressure in the water is very likely to kill a human and the increase is guaranteed to cause an extremely painful death as your body will be crushed by such high pressures. Another reason is worrying about the animals that do live down in the trench. Being in the Mariana trench with limited food supply for the fishy competitors, you would be counted as one of the few food sources down there. Furthermore these are the reasons why humans have not gone down to the Mariana trench more than twice.