Final answer:
Francesca is likely to have difficulty becoming and staying thin due to factors such as inactivity, genetics, metabolism, and the body's set point. Obese people can struggle to lose weight due to their bodies becoming more efficient when caloric intake is reduced.
Step-by-step explanation:
When dieting, Francesca is most likely to have difficulty becoming and staying thin because of a combination of factors including inactivity, genetics, metabolism, and the body's set point (ideal weight). When a person cuts caloric intake, the body reacts as if it is starving and becomes more efficient, making it harder to lose weight. Obese people may also have difficulty in losing weight because of the adaptation of their bodies to certain weights and the fact that they often consume more calories than they burn.