Question

What would be the limiting factor for ATP production by glycolysis in a strenuously exercising muscle that lacks lactate dehydrogenase? increased acidity from lactic acid, causing muscle damage the supply of NAD+ the supply of ADP the supply of pyruvate the supply of

Answer 1

the supply of NAD+.

Step-by-step explanation:

Glycolysis is the first collection of reactions in the metabolism of glucose in muscle cells. This process creates glucose-based pyruvate while producing a few molecules of ATP and NADH. On the other hand, lactate dehydrogenase is an enzyme that is used to extract pyruvate from lactate in the fermentation process.

Muscles would lack sufficient oxygen during strenuous exercises and would therefore proceed to the formation of anaerobic lactate, which uses the enzyme, lactate dehydrogenase. If this enzyme is absent in the process, there would be no production of lactate and no replenishment of NAD+ levels. This would ultimately result in a limited supply of NAD+, which is needed in some glycolytic reactions as electron recipients.