Question

g Deficiencies in glucose 6‑phosphate dehydrogenase frequently present as anemia. Glucose 6‑phosphate dehydrogenase catalyzes in the pentose phosphate pathway. A deficiency in glucose 6‑phosphate dehydrogenase causes a dearth of in all cells, but this is particularly problematic in red blood cells because they lack mitochondria. Its primary role in red blood cells is to maintain levels of Red blood cells with low levels of this compound are more susceptible to

Answer 1

Its primary role in red blood cells is to maintain levels of red blood cells with low levels of this compound are more suceptible to oxidative damage.

Step-by-step explanation:

Pentose phosphte pathway helps in the formation of reducing equivalent named NADPH.

The so formed NADPH is used to maintain a normal cellular level of glutathione which act as antioxidant.

As glutathione is not mantained in its normal level, it ability to reduce to adverse effect of hydrogen peroxide is cut down.

As a result cell is more suceptible to oxidative damage.