Answer:
The correct answer is 2 Aldosterone has nuclear receptors inside the kidney cells and activates gene expression.
Step-by-step explanation:
Aldosterone is a steroid hormone as a result it is lipophilic in nature.Aldosterone is a mineralocorticoid secreted from adrenal cortex.
As it is lipophilic aldosterone can cross the plasma membrane and binds to the nuclear inside the kidney cell which ultimately result in the genes encoding proteins that stimulate water and Na+ ions conservation by the kidneys.