Many of Joe's signs and symptoms can be related to the loss of glucose in his urine. Normally, urine does not contain glucose. When plasma glucose levels are elevated, however, some of the glucose from the plasma passes into the urine. Apply the principle of osmosis to explain why Joe was getting up all night to use the bathroom and why he has low blood pressure and signs of dehydration.
Choose the most accurate explanation for Joe's problem.
A. The frequent urination is happening because the urine contains a large volume of glucose. The loss of glucose from his plasma has decreased his blood volume.
B. The frequent urination is happening as part of a feedback loop to regulate his blood volume. It does not have anything to do with his plasma glucose.
C. The frequent urination is happening because his kidneys have stopped working. The kidney failure leads to low blood pressure.
D. The frequent urination is happening because when glucose moved into his urine, water also followed it. This removed water from his plasma, decreasing his blood volume and dehydrating him.