Question

AGACAGACG-AGACGGACG

If the mutated DNA were transcribed and translated into a protein, which of the following would be true?
A. The mutation would not affect peptide production.

B. One amino acid would change due to an insertion.

C. One amino acid would change due to a substitution.

D. Multiple amino acids are changed due to a frameshift mutation.​

Answer 1

The transcription and translation into protein of the information of a mutated DNA could lead to an amino acid change due to substitution.

Step-by-step explanation:

Substitution is a type of molecular mutation —point mutation— in DNA, with effects on protein synthesis.

The change of an adenine base by guanine in the DNA leads to an erroneous transcription, which results in the change of an amino acid, alanine instead of valine:

Unmutated DNA AGACAGACG

Transcribed mRNA UCU GUC UGC

Amino acids Ser Val Cys

Mutated DNA AGACGGACG

Mutated mRNA UCU GCC UGC

Amino Acids Ser Ala Cys

This change corresponds to a subtitution of one base for another in ADN, leading to a change in an amino acid of the protein and can lead to structural and functional alterations of the synthesized protein

The other options are not correct because:

A. The mutation would affect the production of peptides by changing an amino acid.

B. The change of the amino acid is not due to an insertion, but to a substitution.

D. The change occurred in one amino acid due to a substitution, not multiple amino acids due to a frame mutation.