Question

A young dog has never had much energy. He is brought to a veterinarian for help, and she decides to conduct several diagnostic tests. She discovers that the dog's mitochondria can use only fatty acids and amino acids for cellular respiration, and his cells produce more lactate than normal. Of the following, which is the best explanation of the dog's condition? A young dog has never had much energy. He is brought to a veterinarian for help, and she decides to conduct several diagnostic tests. She discovers that the dog's mitochondria can use only fatty acids and amino acids for cellular respiration, and his cells produce more lactate than normal. Of the following, which is the best explanation of the dog's condition? His cells cannot transport NADH from glycolysis into the mitochondria. His cells have a defective electron transport chain, so glucose goes to lactate instead of to acetyl CoA. His cells lack an essential enzyme in glycolysis so they cannot produce pyruvate. His mitochondria lack the transport protein that moves pyruvate across the outer mitochondrial membrane. His cells contain something that inhibits oxygen use in his mitochondria.

Answer 1

His mitochondria lack the transport protein that moves pyruvate across the outer mitochondrial membrane

Step-by-step explanation:

Glucose is converted to two molecules of pyruvate. The pyruvate formed is transported by the transport protein pyruvate translocase for decorboxylation to produce acetyl-CoA in the mitochondria.

The acetyl-CoA formed undergoes oxidative phosphorylation, electron transport chain and chemiosmosis which helps it enters the Krebs cycle to produce ATP needed for energy

Note:

If the transport chain is absent, the metabolism of fats and amino acids occurs as glucose/carbohydrate cannot be completely oxidized