Loss of interests. Blood Shot (red) eyes, dilated pupils, sniffling, itching, injection marks, puffy face, unusual skin color are all noticeable signs of use and abuse. Blood Shot (red) eyes, dilated pupils, sniffling, itching, injection marks, puffy face, unusual skin color are all noticeable signs of use and abuse. Rapid Mood Swings. Reclusive and Private Behavior. Erratic Behaviors. And changes in their sleep patterns.