Final answer:
The Trail of Tears started in Georgia and ended in Indian Territory., which is the second option provided in the question causing the deaths of thousands of Cherokee due to harsh conditions.
Step-by-step explanation:
The Trail of Tears began in Georgia and ended in Indian Territory, which is present-day Oklahoma. The Cherokee, along with other tribes that were part of the Five Civilized Tribes, were forced to leave their ancestral lands by the Indian Removal Act of 1830, leading to a treacherous and deadly journey. An estimated 4,000 to 5,000 Cherokee people lost their lives due to starvation, disease, and exposure during this relocation.