Answer:
Cigarette smoking is a public health issue because it contributes to a high number of deaths each year is the correct answer.
Step-by-step explanation:
According to the provided information, smoking leads to more than 480,000 deaths each year. The excerpt also explains the diseases caused by smoking, such as lung cancer, and that it causes more deaths than HIV and alcohol used combined. Due to all these facts, the correct answer is the first one.