Answer:
A cell that has Damaged p53 gene , A) may become Cancerous; B) may experience uninhibited and out of control cell division; C) may accumulate multiple mutation.
Step-by-step explanation:
- p53 gene is a tumor suppressor gene that encodes a polypeptide that acts as a transcription factor.
- Mutation in p53 is associated with 50% of human cancers.
- Loss of p53 removes DNA damage check point.
- Mutation in p53 prevents DNA repair and the apoptosis of cells that contain irreparable damage.
- as a result the cells may accumulate multiple mutations.
- Since Functional p53 promotes DNA repair and arrest the cell cycle if a damaged DNA is present; any mutation in p53 may result in uncontrolled cell growth and tumor formation.