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Afrikaners are a Southern African ethnic group descended from a very few Dutch settlers first arriving in the seventeenth and eighteenth centuries. The small population size of the original settlers meant that the colony probably had reduced genetic variation as well as a non-random sample of the genes from the original Dutch population. Today, the Afrikaner population has an unusually high frequency of the gene that causes Huntington's disease, a disease that causes the progressive breakdown of nerve cells.

Explain, using the principles of genetic inheritance, why Huntington's disease is common among the Afrikaners.
A) The only contact the Afrikaners have is with members of their own community.
B) The original Dutch colonists just happened to carry the gene for Huntington's disease with unusually high frequency.
C) The allele for Huntington's disease is dominant and there are no other alleles that can mask the effects of the disease.
D) There was little outside genetic input to their population from immigration so the gene pool stayed exactly the same over the years

User Swaff
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2 Answers

5 votes

Answer:

Step-by-step explanation:

B

User Wheelie
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Answer:

The correct option is B. The original Dutch colonists just happened to carry the gene for Huntington's disease with unusually high frequency .

Step-by-step explanation:

In biology, the founder effect is a term which is used to describe the loss of genetic variation in a small population which has migrated from its larger population. No matter what the original, larger population looked like, the migrated, smaller population will have lesser variations. As a result, the small migrated population will have a completely different genotype as well as phenotype from the original population.

For example, In the above-mentioned question, the original Dutch colonists had an abundance of the genes for Huntington's disease. Hence, it was transferred to the Afrikaners from them as they had very fewer variations.

User Everlasto
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