Question

Reabsorption of nutrients like glucose and amino acids takes place in the proximal convoluted tubule (PCT) via cotransporters that utilize secondary active transport. Which of the following would stop the reabsorption of glucose at the apical surface of the cells in the PCT?A. increasing Na+ concentration in the filtrate.B. loss of K+ leak channels at the apical surface.C. increasing Na+ in the interstitial fluid.D. loss of Na+-K+ ATPase in the basolateral surface of PCT cells.

Answer 1

d. Loss of Na K ATPase in the basolateral surface of PCT cells.

Step-by-step explanation:

Remember the sodium - potassium bump is the responsible to transport some substances in the proximal convoluted tubule, like the glucose and the amino acids, due to the diet the quantity of potassium of sodium can increase, but if the sodium concentration outside the cell is always higher than inside, the bump will works, as the potassium concentration in the inside part of the cell, need to me higher than in the outside part, so the bump will work. And the transport of the substances will be due to the enzyme ATPase, so if the bump works, the enzyme will continue with it works.

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