Answer:
1. They killed, raped and enslaved thousands of natives. Appropriated the land and establishing their own colonies. It was an impact on the native culture, the soil and the climate. Was one of the first genocides.
2. They carried to the land diseases such as syphilis, activated by the sexual mix of both cultures. And other deadly diseases such as smallpox, malaria, cholera, yellow fever, mumps, rubella, leprosy, and canine rabies. Both European colonizers and Native people died for it.
3. They introduced the bread and sugar
4. They brought farm animals: cows, chickens, and horses
5. They created the miscegenation.