Question

A mutation creates a dominant negative allele of a particular gene. The gene encodes a protein that forms a trimer within the cell. If one or more of the subunits has the mutant structure, the entire trimeric protein is inactive. In a heterozygous cell, if the proteins of both alleles are present at the same levels, what percent of the trimers present in the cell will be active?

a. 100%
b. 87.5%
c. 50%
d. 33%
e. 12.5%

Answer 1

The correct answer is 12.5%

Step-by-step explanation:

Answer 2

e. 12.5%

Step-by-step explanation:

There are 12.5 % percent of the trimers present in the cell will be inactive for a heterozygous individual, If atleast one of the subunits has mutant gene.