Question

Base analogs, such as bromouracil, cause mutations in the DNA because they Select one: a. resemble purines and pyrimidines, thus they can be incorporated into DNA in place of normal bases during replication b. add methyl or ethyl groups to the DNA bases causing them to degrade during replication c. insert their multiple ring structure between the DNA bases thus stretching the DNA and causing extra bases to be added during replication d. cause deamination of the DNA resulting in transitions of the nucleotides

Answer 1

They insert their multiple ring structure between the DNA bases thus stretching the DNA and causing extra bases to be added during replication

Step-by-step explanation:

Some base analogs for example bromouracil causes a change or mutation by altering the nitrogenous bases in the DNA strand that has stopped replicating. These dimers cause a distortion in the DNA structure and lead to errors during replication processes. Extra phosphodiester bonds are formed, this process may also lead to the halting or transcription process from the DNA to RNA.

Answer 2

a

Step-by-step explanation:

Bromouracil can pair with both adenine and guanine. Therefore when incorporated in the DNA and copied, it will be sometimes be copied as a thymine and others as a cytosine.

BrU-A => T-A

BrU-G => C-G