Answer:
DNA replication is initiated by the help of these enzymes.
Step-by-step explanation:
Helicase enzyme helps is unwinding the two complementary strand of DNA by hydrolysing the hydrogen bonds present between the nitrogenous bases of the two opposite strands.
Topoisomerase enzyme help in expansion of the Replication bubble by releasing the super coiling or tension occured while unwinding by helicase. It breaks the phosphate bonds in one of the two strands ahead of replication bubble or fork to release super coiling or overwinding.
Single-strand binding proteins gets bind to the separated strands to stabilize the structure of Replication bubble or to keep the both strand separated from each other.