Answer:
Replication would not occur on either the leading or lagging strand.
Step-by-step explanation:
In DNA replication in E. coli, the enzyme primase is used to attach a 5 to 10 base ribonucleotide strand complementary to the parental DNA strand. The RNA strand serves as a starting point for the DNA polymerase that replicates the DNA. If a mutation occurred in the primase gene, replication would not occur on either the leading or lagging strand.