Answer:
Stratum basale
Step-by-step explanation:
Stratum basale is the deepest layer of the epidermis. It is composed of a single layer of cuboidal or columnar keratinocytes. There are some stem cells in stratum basale which divide and add new keratinocytes to the layer. Keratinocytes are the cells with large nuclei and have cytoplasm rich in ribosomes. The stratum basale layer is responsible for the generation of new skin cells. Any serious injury to this layer of the epidermis makes the person unable to regenerate the new skin cells.