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Is the acid-catalyzed hydrolysis of acetamide a reversible or an irreversible reaction?

User Myk Willis
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Answer:

Acid catalyzed hydrolysis of acetamide is irreversible

Step-by-step explanation:

Acid-catalyzed hydrolysis of acetamide is an irreversible process.

All the steps in the hydrolysis of acetamide are reversible except the penultimate step.

Because in the penultimate step, an irreversible acid-base reaction occurs between acetic acid and ammonia. Equilibrium position of this acid-base reaction lies almost completely towards right. Therefore, this irreversible step alone makes hydrolysis of acetamide irreversible as a whole.

Mechanism of hydrolysis has been shown below.

Is the acid-catalyzed hydrolysis of acetamide a reversible or an irreversible reaction-example-1
User Rosesr
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