Answer:
The endoplasmic reticulum is expected to be the first organelle with a protein destined to be secreted from a cell.
Step-by-step explanation:
The rough endoplasmic reticulum is in charge of the synthesis and transport of the proteins destined for secretion. It is also in charge of the latest protein modifications after transduction. Synthesis of proteins might start in the cytoplasm with the production of a molecule portion known as a signal sequence. This portion leads the synthesizing protein and associated ribosome to a specific region in the Rough endoplasmic reticulum where it continues the protein building. Here it also happens the protein folding and the initial stages of glycosylation.
Once proteins are synthesized in the endoplasmic reticulum, they are packaged and sent to the Golgi complex in vesicles, where it happens the final association of carbohydrates with proteins. Finally, protein is transported from the Golgi complex to the embrane and to its final destiny.