Answer:
480
Step-by-step explanation:
INSTRUCTOR
This is:-
I,
N
S
T T
R R
U
C
O
Vowels are - I, O, U
They are written in alphabetical order.
Both T's have to be in start or end.
Also, there must be 2 consonants between each vowel
So,
Case:1 - T T ... I _ _ ... O _ _ .. U ...
Where, ... represents the available spaces (4)
_ is the fixed spots
Case:2- .. I _ _ ... O _ _ .. U ...T T
Thus,

2 is as there are 2 cases
4 is because 4 available spaces and one can go each time
for rest alphabets in which R appear 2 times