Answer:
Option B , hormone paracrine
Step-by-step explanation:
All the signals that are released from hormones usually act on some distant site.
Endocrine signals releases hormones that act on target cell at large distances. These large distance signals move to the target cell through bloodstream. However, transmission through body fluid is a slow process.
Endocrine glands such as thyroid gland etc. release ligands that are produced in one part of the body but affect other body regions some distance away.
Thus option B is correct