Question

Addison's disease is a disorder that results from a reduction in production of glucocorticoids and mineralocorticoids. Individuals with Addison's disease suffer from a variety of systemic symptoms including: muscle weakness, fever, issues with the gastrointestinal tract, and increased tanning. Considering this information, what type of signaling do you think that glucocorticoids and mineralocorticoids stimulate? A. Direct contact B. Paracrine C. Endocrine D. Synaptic E. Autocrine

Answer 1

C. Endocrine

Step-by-step explanation:

In endocrine signalling cells send signals or hormones over long distances. Hence the hormone can be produced at one part of the body and the effect can be observed at entirely different part of the body.

Addison's disease is an endocrine disorder characterised by fatigue, muscle weakness, darkening of skin etc. In the disease, adrenal glands do not produce sufficient amount of hormones cortisol and aldosterone. Cortisol is a glucocorticoid whereas aldosterone is a mineralocorticoid. Together these hormones travel in the body and affect many body functions like

• maintaining blood pressure
• regulating macro molecule metabolism
• balancing insulin effects
• maintaining water and salt balance in body