Question

Which of the following accurately identifies the chemical basis of Chargaff's rule?

the ionic interactions of the negatively charged phosphates with positively charged histone proteins
the presence of deoxyribose instead of ribose
the covalent bonding of the sugar-phosphate backbone
the hydrogen bonding properties of the DNA bases

Answer 1

The chemical basis of Chargaff"s rule is the bonding properties of the DNA bases.

Step-by-step explanation:

According to the Chargaff"s rule in a DNA molecule the total number of purine bases are equal with the total number of pyrimidine bases that means

Adenine +Guanine=Thymine +Cytosine

In simple words the rule is based on the 1:1 ratio of both purine and pyrimidine bases.