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How can enzymes active site become denatured?

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Answer:

Enzymes can become denatured when subject to very high temperatures and pH

Step-by-step explanation:

  • Enzymes are biochemical catalysts that speed up chemical reactions.
  • Some of the characteristics of enzymes are that they are substrate-specific and work at optimum pH and temperature.
  • Enzymes will thus work best at the optimum pH and temperature to yield maximum products.
  • However, when subjected to extreme temperature and pH, they are denatured such that the configuration of active sites changes making it difficult for the substrate to fit in the active sites.

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