Question

Atorvastatin is sold under the trade name Lipitor and is used for lowering cholesterol. Annual global sales of this compound exceed $13 billion. Assign a configuration to each chiral center in atorvastatin: In the boxes below, first input the numbers corresponding to the chiral centers in numerical order as a comma separated list (e.g., "1,3,4"). Then input the configurations of the chiral centers in the same order and format (e.g., "R,S,S"). chiral center(s): Configuration(s):

Answer 1

Atorvastatin has two chiral centers. The question doesn't include the box where have to answer but I can show you in an image where are located and their configuration.

Step-by-step explanation:

The first image shows the chemical structure of atorvastatin and their chiral centers identified as 1 and 2 respectively.

The second image shows the Fischer projections corresponding to every chiral carbon 1 and 2. I wrote R so suggest that there are more carbon atoms forward but not only corresponds to carbon atoms.

You can see that the chiral carbon 1 has R configuration due to the direction from the main substituent to the second follow the clockwise.

The chiral carbon 2 has S configuration due to the direction from the main substituent to the second one go anticlockwise.