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______________ in mammals renders females functionally hemizygous (like males, they only have one active X chromosome in each cell).

User Yogster
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Answer:

X-chromosome inactivation

Step-by-step explanation:

In mammals, females have two copies of X chromosomes while the males have one X and one Y chromosome as their sex chromosomes. The presence of two copies of the X chromosome in females means the presence of double the number of X-linked genes in them as compared to the males. However, during embryonic development, one of the two X chromosomes is inactivated in the cells of females.

The inactivated X chromosome is present as a Barr body in the nucleus. X chromosome inactivation is a random process and either paternal or maternal X chromosome can be inactivated. The process of inactivation of the X chromosome in females balances the dosage of X linked genes among males and females.

User Pete Garafano
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