Question

The enzyme ATCase (aspartate transcarbamoylase) catalyzes the first step in the multi-step synthesis of pyrimidine (single ring) nucleotides. CTP, a pyrimidine, is an inhibitor of ATCase. This is an example of _____. competitive inhibition feedback inhibition

Answer 1

Feedback inhibition

Step-by-step explanation:

Feedback inhibition is one of the mechanisms that regulate the activities of enzymes. In feedback inhibition, accumulation of the product of a multistep metabolic pathway inhibits the enzyme of the first reaction of the metabolic pathway. Aspartate transcarbamoylase is an allosteric enzyme and catalyzes the formation of N-Carbamoylaspartate from aspartate. The enzyme is inhibited as the end product of the pathway, that is, CTP (Cytidine 5'-triphosphate) is accumulated in cells. This is also called end-product inhibition.