Answer:
Option (1).
Step-by-step explanation:
IACUC (Institutional Animal Care and Use Committee) is the group that determines the research facilities keep the accordance of the animal welfare act. The ethical issue must be related to animals.
To proceed any research U.S.federal regulation needs approval of IACUC. The research team requires the approval of IACUC for the research proposal before starting his research on the animals. Researchers must follows the protocols made by IACUC.
Thus, the correct answer is option (1).