The correct answer to this open question is the following.
One major problem that has resulted from globalization in the 20th and 21st centuries is that disease pandemics have become more difficult to contain in a single region.
The constant communication, traveling, and trade of goods due to a globalized world has resulted in an open path where all kinds of viruses and diseases can travel around the world. The best example is the health crisis the world is living right now with the coronavirus and the fear and anxiety in most societies of the world.