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Why are tortoiseshell cats female? Why are tortoiseshell cats female?

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Final answer:

Female tortoiseshell cats exhibit two different coat colors due to X inactivation during embryonic development, while male cats do not.

Step-by-step explanation:

In cats, tortoiseshell fur color is linked to the X chromosome. Female cats have two X chromosomes, while male cats have one X and one Y chromosome. During embryonic development, one of the X chromosomes in female cats randomly inactivates in each cell, resulting in a tortoiseshell pattern if the cat has two different alleles for coat color.

For example, if a female cat has one X chromosome with a black allele and another X chromosome with an orange allele, some cells will activate the black allele and display black fur, while other cells will activate the orange allele and display orange fur. This results in the characteristic tortoiseshell coat pattern.

Male cats, on the other hand, only have one X chromosome and therefore do not have the same variation in coat color as female tortoiseshell cats.

User Bhollis
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Answer:

All tortoiseshell and tortoiseshell and white (Calico) cats are female. But not all gingers are male, though most are. The reason is that in cats the colour gene is carried on the X chromosome. As females have two Xs they can express two colours in the coat, and if black is inherited from one parent and ginger (red) from the other, the result is a calico cat. The calico's brother, having only one X chromosome, would be either ginger or black, depending on the colour of the mother. I believe there was a case of an apparently male calico cat but it was found to have a mutation giving an XXY chromosome set-up, and was sterile. For a female to be ginger she would have to inherit red from both parents. This could happen if the father was ginger and the mother tortoiseshell for example. The white is inherited on a separate gene and is independent of the colour gene. It can appear on either gender and with any colour of coat. For some reason not understood it is usually found that in tortoiseshell and white cats the patches of black and ginger are larger and more distinct than in the plain tortoiseshell without white. A tabby pattern of stripes can also be inherited separately, resulting in a cat known as a "torby" (Tabby-tortoiseshell).

Step-by-step explanation:

User Opetroch
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